Salmon farming is a rapidly expanding industry. In order for it to develop in an ethical manner, many ethical issues must be confronted. Among these are questions regarding the quality of life of salmon on farms. To develop reasonable answers to these questions considerable thought must be devoted to developing appropriate standards of care for salmon. If these questions are not addressed the results could be bad both for salmon and for salmon farmers.

The caliber of recent discourse regarding geneticallymodified organisms (GMOs) has suffered from a lack of consensuson terminology, from the scarcity of evidence upon which toassess risk to health and to the environment, and from valuedifferences between proponents and opponents of GMOs. Towardsaddressing these issues, we present the thesis that GM should bedefined as the forcible insertion of DNA into a host genome,irrespective of the source of the DNA, and exclusive ofconventional or mutation breeding.Some defenders of the commercial use of GMOs (...) have referred to thescientific work of GMO critics as ``junk science.'''' Such a claim isfalse and misleading, given that many papers critical of both theutility and safety of GMOs have been published in peer reviewedjournals by respected scientists. In contrast, there is a dearthof peer reviewed work to substantiate the frequently heardassertions of either safety or utility in GMOs. The polarity,which now characterizes much of the public discourse on GMOs,reflects not simply scientific disagreement, but alsodisagreement in underlying value assumptions. Value differencesstrongly affect the assessment of both benefit and harm fromGMOs. (shrink)

In the text book treatise on certitude, there usually appears a line in definition of "certitude mere subjectiva," which is, for practical purposes, one of the most important in the book. As an example of what thought and imagination can do to enlarge upon and embelish the outline of class instruction and to ground philosophy deeper in the mind, Mr. Harkins presents this paper, an admirable development of the few short words of the definition which we are so prone to (...) introduce to the memory and then dismiss for good. (shrink)

The current paper provides readers some clarifications on the nature and goals of mass media campaigns designed to promote organ donation. These clarifications were necessitated by an earlier essay by Rady et al. (Med Health Care Philos 15:229–241, 2012) who present erroneous claims that media promotion campaigns in this health context represent propaganda that seek to misrepresent the transplantation process. Information is also provided on the nature and relative power of media campaigns in organ donation promotion.

This paper argues that professionals who make boundary-related decisions should be guided by relationship-based practice. In our roles as service users and professionals, drawing from our lived experiences of professional relationships, we argue we need to move away from distance-based practice. This includes understanding the boundary stories and narratives that exist for all of us – including the people we support, other professionals, as well as the organisations and systems within which we work. When we are dealing with professional boundary (...) issues, we should centre relationship-building skills that are central to many other aspects of our work. Skills that foster relationships at all levels – between professionals, service users, and services – need to be revalued. Our final recommendation is to create, develop, and foster safer spaces within and outside of organisations, as well as inter-professionally, for the discussion and exploration of boundary-related issues and practice. We are interested in hearing from those with experiences of being marginalised by boundaries so that they can inform a reshaping of our collective ideas around boundary related practices. To foster relationship-based practices in organisations, we have outlined several recommendations here; however, we recognize that these do not go far enough, and that collective action is needed to inform systemic change. (shrink)

Uncoupling proteins (UCPs) regulate mitochondrial function, and thus cellular metabolism. Angiotensin‐converting enzyme (ACE) is the central component of endocrine and local tissue renin–angiotensin systems (RAS), which also regulate diverse aspects of whole‐body metabolism and mitochondrial function (partly through altering mitochondrial UCP expression). We show that ACE expression also appears to be regulated by mitochondrial UCPs. In genetic analysis of two unrelated populations (healthy young UK men and Scandinavian diabetic patients) serum ACE (sACE) activity was significantly higher amongst UCP3‐55C (rather than (...) T) and UCP2 I (rather than D) allele carriers. RNA interference against UCP2 in human umbilical vein endothelial cells reduced UCP2 mRNA sixfold (P < 0·01) whilst increasing ACE expression within a physiological range (<1·8‐fold at 48 h; P < 0·01). Our findings suggest novel hypotheses. Firstly, cellular feedback regulation may occur between UCPs and ACE. Secondly, cellular UCP regulation of sACE suggests a novel means of crosstalk between (and mutual regulation of) cellular and endocrine metabolism. This might partly explain the reduced risk of developing diabetes and metabolic syndrome with RAS antagonists and offer insight into the origins of cardiovascular disease in which UCPs and ACE both play a role. (shrink)

Hugh Lacey (1939) é pesquisador emérito na Swarthmore College, Pennsylvania, Estados Unidos, onde começou a lecionar em 1972. É Doutor em História e Filosofia da Ciência pela Universidade de Indiana (EUA), tendosido professor visitante na Universidade de São Paulo em diversas ocasiões (1973, 1996, 2000 e 2004). Seus trabalhos atribuem lugares próprios aos valores dentro da tecnociência, procurando mostrar que a abordagem científica materialista precisa assumir também o lugar que as coisas ocupam em sistemas ecológicos e sociais. Lacey é autor (...) de diversos artigos e livros, entre os quais estão Valores e Atividade Científica 1, Valores e Atividade Científica 2, A Controvérsia sobre os transgênicos: questões científicas e éticas, entre outros. (shrink)

Valid consent requires the potential research participant understands the information provided. We examined current practice in 50 proposed Clinical Trials of Investigational Medicinal Products to determine how this understanding is checked. The majority of the proposals ( n = 44) indicated confirmation of understanding would take place during an interactive conversation between the researcher and potential participant, containing questions to assess and establish understanding. Yet up until now, research design and review have not focussed upon this, concentrating more on written (...) material. We propose ways this interactive conversation can be documented, and the process of checking understanding improved. (shrink)

Studies examining the ways in which the training of engineers and scientists shapes their research strategies and scientific identities.

Research consent processes must provide potential participants with the necessary information to help them decide if they wish to join a study. On the Oxford ‘A’ Research Ethics Committee we’ve found that current research proposals mostly provide adequate detail (even if not in an easily comprehensible format), but often fail to support decision making, a view supported by published evidence. In a previous paper, we described how consent might be structured, and here we develop the concept of an Information and (...) Decision Aid (IDA) that can support decision making and be used to guide the dialogue between researcher and potential participant. Our proposal requires limited changes to current processes or paperwork and would provide an easily accessible document for others that the potential participant might approach for advice. It could later be integrated with the Informed Consent Form to ensure all matters of concern to the individual participant have been addressed before consent is formally signed off. (shrink)

Previous research investigating perception of science and scientists indicates that certain physical, behavioural and belief system–related attributes are associated with scientists. Some of these include white, male, reserved and devoted to work. The current research takes an international approach into perceptions of science and scientists related to (non-)religious social identity. Four studies ( n = 1146) across four countries (the United Kingdom, Germany, Spain, Argentina) investigates perceptions of scientists with religious social identity. This research included several targets with multiple identities, (...) combining (non-)religious identity (religious, spiritual, atheist, non-religious or none specified) and scientist identity (scientist or evolutionary scientist). Findings show that the perceiver’s own (non-)religious social identity relates to their view of scientists. In addition, exploration of trust in scientists with differing (non-)religious identities by personal (non-) religious identification revealed not only an in-group bias, but an overarching bias towards a scientist without any (non-)religious identification, which provides an interesting avenue to further explore. (shrink)

This study examined self-recognition processing in both the auditory and visual modalities by determining how comparable hearing a recording of one’s own voice was to seeing photograph of one’s own face. We also investigated whether the simultaneous presentation of auditory and visual self-stimuli would either facilitate or inhibit self-identification. Ninety-one participants completed reaction-time tasks of self-recognition when presented with their own faces, own voices, and combinations of the two. Reaction time and errors made when responding with both the right and (...) left hand were recorded to determine if there were lateralization effects on these tasks. Our findings showed that visual self-recognition for facial photographs appears to be superior to auditory self-recognition for voice recordings. Furthermore, a combined presentation of one’s own face and voice appeared to inhibit rather than facilitate self-recognition and there was a left-hand advantage for reaction time on the combined-presentation tasks. (shrink)

This study examined the approaches used by two preservice elementary school teachers as they designed and taught antiracist social studies lessons about civil rights history during a community-based field experience. Using a theoretical framework of racial pedagogical content knowledge (RPCK), we identified three domains of RPCK needed to enact antiracist elementary social studies teaching and analyzed how these domains surfaced during lessons and interviews. Our cross-case analysis revealed that both preservice teachers struggled to balance presenting civil rights events as historically (...) significant while also calling their legacy into question. However, the preservice teacher who fostered dialogic and student-centered discussions was ultimately more successful with antiracist teaching. We provide implications for supporting elementary school teachers in developing social studies lessons that embody antiracism and teach the long civil rights movement. (shrink)

This long-awaited book replaces Hughes and Cresswell's two classic studies of modal logic: _An Introduction to Modal Logic_ and _A Companion to Modal Logic_. _A New Introduction to Modal Logic_ is an entirely new work, completely re-written by the authors. They have incorporated all the new developments that have taken place since 1968 in both modal propositional logic and modal predicate logic, without sacrificing tha clarity of exposition and approachability that were essential features of their earlier works. The book (...) takes readers from the most basic systems of modal propositional logic right up to systems of modal predicate with identity. It covers both technical developments such as completeness and incompleteness, and finite and infinite models, and their philosophical applications, especially in the area of modal predicate logic. (shrink)

Some authors reject what they call the "Simple View"---i.e., the principle that anyone who A's intentionally intends to A. My purpose here is to defend this principle. Rejecting the Simple View, I shall claim, forces us to assign to other mental states the functional role of intention: that of providing settled objectives to guide deliberation and action. A likely result is either that entities will be multiplied, or that the resultant account will invite reassertion of reductionist theories. In any case, (...) the account must drive a wedge between intention and practical rationality, by forbidding agents to intend goals it is rational to seek. Worse yet, the states it "substitutes" for intention turn out to be subject to the same constraints that prompted the substitution, and hence are indistinguishable from intention in the very respect in which they are alleged to differ. Thus, I shall argue, there is no evidence to justify such supposed distinctions, and the Simple View is to be preferred. (shrink)

I initiate the concept of ‘making-remote’ to capture various strategies for representing the human in late Palaeolithic cave art. Drawing out the role of remoteness within phenomenological accounts of perception (Husserl and Merleau-Ponty), as well as offering an analysis of a wide range of archaeological evidence, I argue that realism does not capture the specificity of these human representations. In contrast to naturalistic animal representations, humans are consistently represented with a high degree of abstraction e.g. schematisation and abbreviation. I also (...) argue for a site-specific distinction between deep caves and rock-shelters. Following Bourdier (2010) and Pinçon (2012), art at sites such as Roc-aux-Sorciers is best understood as stylised ‘public art’. Meanwhile, the highly expressive and realist art of La Marche is domestic in contrast to the exclusively symbolic art of deep caves. In conclusion I argue that ‘making-remote’ in cave art’s human representations exhibits complex relations to self and others. (shrink)

It is not infrequently said that the true justification of moral beliefs lies in theology. I wish here to examine precisely what is meant by this contention, and by what arguments, if any, it can be substantiated. The view I am examining is not that the only valid reason for doing what is right is a theological reason ; as if we could know independently of theology what was right, but required a theological motive to make it reasonable to do (...) it. It is rather that the very fact that it is right is logically dependent on certain facts of a theological nature; or, to express the matter otherwise, that from certain theological propositions it is possible validly to draw certain conclusions in the form of propositions which state what I ought to do, and that this fact is the source of the validity of these latter propositions. This, however, is not yet a sufficiently precise account of the theory in question, since it might cover a number of different contentions, some of which I think may be reasonably maintained, while others, I think, may not. I propose to work towards a clearer formulation by considering certain arguments which have been advanced in order to deny outright the very possibility of arguing validly “from theology to ethics”; for I do believe that these arguments prove something , and rule out certain theories as untenable. (shrink)

A legitimação de políticas públicas que apóiam o cultivo de lavouras transgênicas em larga escala pressupõe, entre outras condições, (1) que os dados empíricos garantem não haver riscos ambientais não-administráveis e, (2) a não-existência de modos melhores de produzir alimentos sem a utilização de técnicas transgênicas. O artigo discute: (a) Os tipos de investigação científica necessários para um exame adequado da condição (1), (b) como as investigações sobre (1) e (2) se relacionam entre si, e (c) como tais investigações se (...) relacionam com valores sociais controvertidos. (shrink)